The Type 2 Diabetes and Insulin-Resistance Locus Near IRS1 Is A Determinant of HDL Cholesterol and Triglycerides Levels Among Diabetic Subjects

OBJECTIVE: SNP rs2943641 near the insulin receptor substrate 1 (IRS1) gene has been found to be associated with type 2 diabetes (T2D) and insulin-resistance in genome-wide association studies. We investigated whether this SNP is associated with cardiovascular risk factors and coronary artery disease...

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Hlavní autoři: Sharma, Rajani, Prudente, Sabrina, Andreozzi, Francesco, Powers, Christine, Mannino, Gaia, Bacci, Simonetta, Gervino, Ernest V., Hauser, Thomas H., Succurro, Elena, Mercuri, Luana, Goheen, Elizabeth H., Shah, Hetal, Trischitta, Vincenzo, Sesti, Giorgio, Doria, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089704/
https://ncbi.nlm.nih.gov/pubmed/21353221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.01.022
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