The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

OBJECTIVE: Obesity and cardiovascular disease recognize a common metabolic soil and may therefore share part of their genetic background. Genome-wide association studies have identified variability at the SH2B1 locus as a predictor of obesity. We investigated whether SNP rs4788102, which captures th...

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Detalhes bibliográficos
Main Authors: Prudente, Sabrina, Morini, Eleonora, Larmon, Jay, Andreozzi, Francesco, Pietro, Natalia Di, Nigro, Angela, Gervino, Ernest V, Mannino, Gaia Chiara, Bacci, Simonetta, Hauser, Thomas H, Bellacchio, Emanuele, Formoso, Gloria, Pellegrini, Fabio, Proto, Vittoria, Menzaghi, Claudia, Frittitta, Lucia, Pandolfi, Assunta, Sesti, Giorgio, Doria, Alessandro, Trischitta, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728428/
https://ncbi.nlm.nih.gov/pubmed/21907990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.08.019
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