The coupling of epidermal growth factor receptor down regulation by 1alpha,25-dihydroxyvitamin D3 to the hormone-induced cell cycle arrest at the G1-S checkpoint in ovarian cancer cells

1alpha,25-dihydroxyvitamin D3, 1,25(OH)(2)D(3), regulates gene expression through the vitamin D receptor. The present studies identify the epidermal growth factor receptor, EGFR, as a target gene suppressed by 1,25(OH)(2)D(3) in human ovarian cancer cells. The suppression was detected at both mRNA a...

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Detalhes bibliográficos
Main Authors: Shen, Zheng, Zhang, Xiaohui, Tang, Jinfu, Kasiappan, Ravi, Jinwal, Umesh, Li, Pengfei, Hann, Shan, Nicosia, Santo V., Wu, Jie, Zhang, Xiaohong, Bai, Wenlong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089697/
https://ncbi.nlm.nih.gov/pubmed/21458521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.02.023
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