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Timeless Links Replication Termination to Mitotic Kinase Activation

The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood. The human Timeless protein (Tim) associates with S phase replication checkpoint proteins Claspin and Tipin, and plays an important role in maintaining replication fork st...

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Autors principals: Dheekollu, Jayaraju, Wiedmer, Andreas, Hayden, James, Speicher, David, Gotter, Anthony L., Yen, Tim, Lieberman, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089618/
https://ncbi.nlm.nih.gov/pubmed/21573113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019596
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