Focal Adhesion Kinase (FAK) Binds RET Kinase via Its FERM Domain, Priming a Direct and Reciprocal RET-FAK Transactivation Mechanism

Whether RET is able to directly phosphorylate and activate downstream targets independently of the binding of proteins that contain Src homology 2 or phosphotyrosine binding domains and whether mechanisms in trans by cytoplasmic kinases can modulate RET function and signaling remain largely unexplor...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Plaza-Menacho, Iván, Morandi, Andrea, Mologni, Luca, Boender, Piet, Gambacorti-Passerini, Carlo, Magee, Anthony I., Hofstra, Robert M. W., Knowles, Phillip, McDonald, Neil Q., Isacke, Clare M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089571/
https://ncbi.nlm.nih.gov/pubmed/21454698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.168500
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares