SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates

The mammalian HRD1-SEL1L complex provides a scaffold for endoplasmic reticulum (ER)-associated degradation (ERAD), thereby connecting luminal substrates for ubiquitination at the cytoplasmic surface after their retrotranslocation through the endoplasmic reticulum membrane. In this study the stabilit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Iida, Yasutaka, Fujimori, Tsutomu, Okawa, Katsuya, Nagata, Kazuhiro, Wada, Ikuo, Hosokawa, Nobuko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Protein Synthesis and Degradation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089536/
https://ncbi.nlm.nih.gov/pubmed/21454652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215871
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