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SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates
The mammalian HRD1-SEL1L complex provides a scaffold for endoplasmic reticulum (ER)-associated degradation (ERAD), thereby connecting luminal substrates for ubiquitination at the cytoplasmic surface after their retrotranslocation through the endoplasmic reticulum membrane. In this study the stabilit...
में बचाया:
मुख्य लेखकों: | , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2011
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089536/ https://ncbi.nlm.nih.gov/pubmed/21454652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215871 |
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