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Measurable impact of RNA quality on gene expression results from quantitative PCR

Compromised RNA quality is suggested to lead to unreliable results in gene expression studies. Therefore, assessment of RNA integrity and purity is deemed essential prior to including samples in the analytical pipeline. This may be of particular importance when diagnostic, prognostic or therapeutic...

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Main Authors: Vermeulen, Joëlle, De Preter, Katleen, Lefever, Steve, Nuytens, Justine, De Vloed, Fanny, Derveaux, Stefaan, Hellemans, Jan, Speleman, Frank, Vandesompele, Jo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089491/
https://ncbi.nlm.nih.gov/pubmed/21317187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr065
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