Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity

To explore the possibility of using restriction enzymes in a synthetic biology based on artificially expanded genetic information systems (AEGIS), 24 type-II restriction endonucleases (REases) were challenged to digest DNA duplexes containing recognition sites where individual Cs and Gs were replace...

Full description

Saved in:
Bibliographic Details
Main Authors: Chen, Fei, Yang, Zunyi, Yan, Maocai, Alvarado, J. Brian, Wang, Ganggang, Benner, Steven A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Synthetic Biology and Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089450/
https://ncbi.nlm.nih.gov/pubmed/21245035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1274
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items