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Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity

To explore the possibility of using restriction enzymes in a synthetic biology based on artificially expanded genetic information systems (AEGIS), 24 type-II restriction endonucleases (REases) were challenged to digest DNA duplexes containing recognition sites where individual Cs and Gs were replace...

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Main Authors: Chen, Fei, Yang, Zunyi, Yan, Maocai, Alvarado, J. Brian, Wang, Ganggang, Benner, Steven A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089450/
https://ncbi.nlm.nih.gov/pubmed/21245035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1274
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