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A Novel Conversion Strategy using an Expanded Genetic Alphabet to Assay Nucleic Acids

Methods to detect DNA and RNA (collectively xNA) are easily plagued by noise, false positives, and false negatives, especially with increasing levels of multiplexing in increasing complex assay mixtures. We describe assay architectures that mitigate these problems, here by converting standard xNA an...

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Detalhes bibliográficos
Main Authors: Yang, Zunyi, Durante, Michael, Glushakova, Lyudmyla G., Sharma, Nidhi, Leal, Nicole A., Bradley, Kevin M., Chen, Fei, Benner, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868369/
https://ncbi.nlm.nih.gov/pubmed/23541235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400422r
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