Conformational Epitopes Recognized by Protective Anti-Neisserial Surface Protein A Antibodies

NspA is a conserved membrane protein that elicits protective antibody responses in mice against Neisseria meningitidis. A recent crystallographic study showed that NspA adopts an eight-stranded β-barrel structure when reconstituted in detergent. In order to define the segments of NspA-containing epi...

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Udgivet i:Infect Immun
Main Authors: Hou, Victor C., Moe, Gregory R., Raad, Zyde, Wuorimaa, Tomi, Granoff, Dan M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.12.6844-6849.2003
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