Functional Activity of Anti-Neisserial Surface Protein A Monoclonal Antibodies against Strains of Neisseria meningitidis Serogroup B

Neisserial surface protein A (NspA) is currently being investigated with humans as a candidate vaccine for the prevention of meningococcal disease. Although NspA is highly conserved, the ability of anti-NspA antibodies to bind to or elicit complement-mediated bactericidal activity against diverse Ne...

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Main Authors: Moe, G. R., Zuno-Mitchell, P., Lee, S. S., Lucas, A. H., Granoff, D. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98387/
https://ncbi.nlm.nih.gov/pubmed/11349041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.3762-3771.2001
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