Conformational Epitopes Recognized by Protective Anti-Neisserial Surface Protein A Antibodies

NspA is a conserved membrane protein that elicits protective antibody responses in mice against Neisseria meningitidis. A recent crystallographic study showed that NspA adopts an eight-stranded β-barrel structure when reconstituted in detergent. In order to define the segments of NspA-containing epi...

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Bibliografiska uppgifter
Huvudupphovsmän: Hou, Victor C., Moe, Gregory R., Raad, Zyde, Wuorimaa, Tomi, Granoff, Dan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Microbial Immunity and Vaccines
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC308938/
https://ncbi.nlm.nih.gov/pubmed/14638771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.6844-6849.2003
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