Deletion of Mycobacterium tuberculosis Sigma Factor E Results in Delayed Time to Death with Bacterial Persistence in the Lungs of Aerosol-Infected Mice

The stress-induced extracytoplasmic sigma factor E (SigE) of Mycobacterium tuberculosis shows increased expression after heat shock, sodium dodecyl sulfate treatment, and oxidative stress, as well as after phagocytosis in macrophages. We report that deletion of sigE results in delayed lethality in m...

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Detalhes bibliográficos
Main Authors: Ando, Masaru, Yoshimatsu, Tetsuyuki, Ko, Chiew, Converse, Paul J., Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC308924/
https://ncbi.nlm.nih.gov/pubmed/14638810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7170-7172.2003
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