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The Saccharomyces cerevisiae Telomerase Subunit Est3 Binds Telomeres in a Cell Cycle– and Est1–Dependent Manner and Interacts Directly with Est1 In Vitro

Telomerase is a telomere dedicated reverse transcriptase that replicates the very ends of eukaryotic chromosomes. Saccharomyces cerevisiae telomerase consists of TLC1 (the RNA template), Est2 (the catalytic subunit), and two accessory proteins, Est1 and Est3, that are essential in vivo for telomeras...

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Detalhes bibliográficos
Main Authors: Tuzon, Creighton T., Wu, Yun, Chan, Angela, Zakian, Virginia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088721/
https://ncbi.nlm.nih.gov/pubmed/21573139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002060
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