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Telomerase and Tel1p Preferentially Associate with Short Telomeres in S. cerevisiae

In diverse organisms, telomerase preferentially elongates short telomeres. We generated a single short telomere in otherwise wild-type (WT) S. cerevisiae cells. The binding of the positive regulators Ku and Cdc13p was similar at short and WT-length telomeres. The negative regulators Rif1p and Rif2p...

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Autors principals: Sabourin, Michelle, Tuzon, Creighton T., Zakian, Virginia A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650483/
https://ncbi.nlm.nih.gov/pubmed/17656141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.07.016
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