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Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast

Telomerase enables telomere length homeostasis, exhibiting increasing preference for telomeres as their lengths decline. This regulation involves telomere repeat-bound Rap1, which provides a length-dependent negative feedback mechanism, and the Tel1 and Mec1 kinases, which are positive regulators of...

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Detalhes bibliográficos
Main Authors: Arnerić, Milica, Lingner, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247385/
https://ncbi.nlm.nih.gov/pubmed/17917674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401082
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