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Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors

The cancer stem cell (CSC) concept is a highly debated topic in cancer research. While experimental evidence in favor of the cancer stem cell theory is apparently abundant, the results are often criticized as being difficult to interpret. An important reason for this is that most experimental data t...

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書誌詳細
主要な著者: Sottoriva, Andrea, Vermeulen, Louis, Tavaré, Simon
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088646/
https://ncbi.nlm.nih.gov/pubmed/21573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001132
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