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Anterior Segment Dysgenesis and Early-Onset Glaucoma in nee Mice with Mutation of Sh3pxd2b

PURPOSE. Mutations in SH3PXD2B cause Frank-Ter Haar syndrome, a rare condition characterized by congenital glaucoma, as well as craniofacial, skeletal, and cardiac anomalies. The nee strain of mice carries a spontaneously arising mutation in Sh3pxd2b. The purpose of this study was to test whether ne...

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Autors principals: Mao, Mao, Hedberg-Buenz, Adam, Koehn, Demelza, John, Simon W. M., Anderson, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088558/
https://ncbi.nlm.nih.gov/pubmed/21282566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5993
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