Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice

PURPOSE: Mutations in the gene encoding collagen type IV alpha 1 (COL4A1) cause multisystem disorders including anterior segment dysgenesis (ASD) and optic nerve hypoplasia. The penetrance and severity of individual phenotypes depends on genetic context. Here, we tested the effects of a Col4a1 mutat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Mao, Mao, Smith, Richard S., Alavi, Marcel V., Marchant, Jeffrey K., Cosma, Mihai, Libby, Richard T., John, Simon W. M., Gould, Douglas B.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2015
Matèries:
Glaucoma
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627250/
https://ncbi.nlm.nih.gov/pubmed/26567795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17527
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars