Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma

Anterior segment dysgenesis (ASD) encompasses a group of developmental disorders in which a closed angle phenotype in the anterior chamber of the eye can occur and 50% of patients develop glaucoma. Many ASDs are thought to involve an inappropriate patterning and migration of the periocular mesenchym...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Martino, Vanessa B., Sabljic, Thomas, Deschamps, Paula, Green, Rebecca M., Akula, Monica, Peacock, Erica, Ball, Alexander, Williams, Trevor, West-Mays, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007979/
https://ncbi.nlm.nih.gov/pubmed/27483349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025262
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