Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells

Considerable details about microRNA (miRNA) biogenesis and regulation have been uncovered, however, little is known about the fate of the miRNA subsequent to target regulation. To gain insight into this process, we carried out kinetic analysis of a miRNA’s turnover following termination of its bioge...

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Bibliographic Details
Main Authors: Baccarini, Alessia, Chauhan, Hemangini, Gardner, Thomas J., Jayaprakash, Anitha, Sachidanandam, Ravi, Brown, Brian D.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088433/
https://ncbi.nlm.nih.gov/pubmed/21353554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.01.067
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