High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

We introduce two large-scale resources for functional analysis of microRNA—a decoy/sponge library for inhibiting microRNA function and a sensor library for monitoring microRNA activity. To take advantage of the sensor library, we developed a high-throughput assay called Sensor-seq, which permits the...

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Bibliografiske detaljer
Main Authors: Mullokandov, Gavriel, Baccarini, Alessia, Ruzo, Albert, Jayaprakash, Anitha D., Tung, Navpreet, Israelow, Benjamin, Evans, Matthew J., Sachidanandam, Ravi, Brown, Brian D.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518396/
https://ncbi.nlm.nih.gov/pubmed/22751203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2078
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