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Impact of Dose De-Escalation and Escalation on Daptomycin's Pharmacodynamics against Clinical Methicillin-Resistant Staphylococcus aureus Isolates in an In Vitro Model

De-escalation and escalation therapeutic strategies are commonly employed by clinicians on the basis of susceptibility results and patient response. Since no in vitro or in vivo data are currently available to support one strategy over the other for daptomycin, we attempted to evaluate the effects o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vidaillac, Celine, Steed, Molly E., Rybak, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088203/
https://ncbi.nlm.nih.gov/pubmed/21321148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01291-10
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