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Impact of Dose De-Escalation and Escalation on Daptomycin's Pharmacodynamics against Clinical Methicillin-Resistant Staphylococcus aureus Isolates in an In Vitro Model

De-escalation and escalation therapeutic strategies are commonly employed by clinicians on the basis of susceptibility results and patient response. Since no in vitro or in vivo data are currently available to support one strategy over the other for daptomycin, we attempted to evaluate the effects o...

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Detalhes bibliográficos
Main Authors: Vidaillac, Celine, Steed, Molly E., Rybak, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088203/
https://ncbi.nlm.nih.gov/pubmed/21321148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01291-10
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