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Evaluation of Telavancin Activity versus Daptomycin and Vancomycin against Daptomycin-Nonsusceptible Staphylococcus aureus in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Daptomycin-nonsusceptible (DNS) Staphylococcus aureus strains have been reported over the last several years. Telavancin is a lipoglycopeptide with a dual mechanism of action, as it inhibits peptidoglycan polymerization/cross-linking and disrupts the membrane potential. Three clinical DNS S. aureus...

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Détails bibliographiques
Auteurs principaux: Steed, Molly E., Vidaillac, Céline, Rybak, Michael J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264278/
https://ncbi.nlm.nih.gov/pubmed/22123693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05849-11
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