Heterologous Plasmid DNA Prime-Recombinant Human Adenovirus 5 Boost Vaccination Generates a Stable Pool of Protective Long-Lived CD8(+) T Effector Memory Cells Specific for a Human Parasite, Trypanosoma cruzi

Recently, we described a heterologous prime-boost strategy using plasmid DNA followed by replication-defective human recombinant adenovirus type 5 as a powerful strategy to elicit long-lived CD8(+) T-cell-mediated protective immunity against experimental systemic infection of mice with a human intra...

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Detalhes bibliográficos
Main Authors: Rigato, Paula Ordonhez, de Alencar, Bruna C., de Vasconcelos, José Ronnie C., Dominguez, Mariana R., Araújo, Adriano F., Machado, Alexandre V., Gazzinelli, Ricardo T., Bruna-Romero, Oscar, Rodrigues, Mauricio M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088135/
https://ncbi.nlm.nih.gov/pubmed/21357719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01190-10
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