FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

Oncogenic activation of the RAS-ERK MAP kinase signaling pathway can lead to uncontrolled proliferation but can also result in apoptosis or premature cellular senescence, both regarded as natural protective barriers to cell immortalization and transformation. In FGFR3-related skeletal dyplasias, onc...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Krejci, Pavel, Prochazkova, Jirina, Smutny, Jiri, Chlebova, Katarina, Lin, Patricia, Aklian, Anie, Bryja, Vitezslav, Kozubik, Alois, Wilcox, William R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087869/
https://ncbi.nlm.nih.gov/pubmed/20362703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2010.03.021
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars