Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence

Neovascularization is a crucial component of tumor growth and ischemia. Although prior work primarily used disease models, delineation of neovascularization in the absence of disease can reveal intrinsic mechanisms of microvessel regulation amenable to manipulation in illness. We created a condition...

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Detaylı Bibliyografya
Asıl Yazarlar: Oladipupo, Sunday S., Hu, Song, Santeford, Andrea C., Yao, Junjie, Kovalski, Joanna R., Shohet, Ralph V., Maslov, Konstantin, Wang, Lihong V., Arbeit, Jeffrey M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Vascular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087536/
https://ncbi.nlm.nih.gov/pubmed/21307392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-307538
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