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Development of IL-22–producing NK lineage cells from umbilical cord blood hematopoietic stem cells in the absence of secondary lymphoid tissue

Human secondary lymphoid tissues (SLTs) contain interleukin-22 (IL-22)–producing cells with an immature NK phenotype. Given their location, these cells are difficult to study. We have generated large numbers of NK22 cells from hematopoietic stem cells. HSC-derived NK22 cells show a CD56(+)CD117(high...

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Autors principals: Tang, Qin, Ahn, Yong-Oon, Southern, Peter, Blazar, Bruce R., Miller, Jeffery S., Verneris, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087531/
https://ncbi.nlm.nih.gov/pubmed/21310921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-303081
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