T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies

T-cell therapy with genetically modified T cells targeting CD19 or CD20 holds promise for the immunotherapy of hematologic malignancies. These targets, however, are only present on B cell–derived malignancies, and because they are broadly expressed in the hematopoietic system, their targeting may ha...

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Detalhes bibliográficos
Main Authors: Shaffer, Donald R., Savoldo, Barbara, Yi, Zhongzhen, Chow, Kevin K. H., Kakarla, Sunitha, Spencer, David M., Dotti, Gianpietro, Wu, Meng-Fen, Liu, Hao, Kenney, Shannon, Gottschalk, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087480/
https://ncbi.nlm.nih.gov/pubmed/21304103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278218
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