Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments

The low frequency of hematopoietic stem and progenitor cells (HSPCs) in human BM has precluded analysis of the direct biochemical effects elicited by cytokines in these populations, and their functional consequences. Here, single-cell phospho-specific flow cytometry was used to define the signaling...

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Bibliografski detalji
Glavni autori: Gibbs, Kenneth D., Gilbert, Penney M., Sachs, Karen, Zhao, Feifei, Blau, Helen M., Weissman, Irving L., Nolan, Garry P., Majeti, Ravindra
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Hematopoiesis and Stem Cells
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087474/
https://ncbi.nlm.nih.gov/pubmed/21357764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-298232
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