Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments

The low frequency of hematopoietic stem and progenitor cells (HSPCs) in human BM has precluded analysis of the direct biochemical effects elicited by cytokines in these populations, and their functional consequences. Here, single-cell phospho-specific flow cytometry was used to define the signaling...

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Detaylı Bibliyografya
Asıl Yazarlar: Gibbs, Kenneth D., Gilbert, Penney M., Sachs, Karen, Zhao, Feifei, Blau, Helen M., Weissman, Irving L., Nolan, Garry P., Majeti, Ravindra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Hematopoiesis and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087474/
https://ncbi.nlm.nih.gov/pubmed/21357764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-298232
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