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Design of peptide inhibitors that bind the bZIP domain of Epstein-Barr virus protein BZLF1

Designing proteins or peptides that bind native protein targets can aid the development of novel reagents and/or therapeutics. Rational design also tests our understanding of the principles underlying protein recognition. This paper describes several strategies used to design peptides to bind to the...

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Autors principals: Chen, T. Scott, Reinke, Aaron W., Keating, Amy E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087387/
https://ncbi.nlm.nih.gov/pubmed/21354428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.046
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