Association of CTNNB1 (β-Catenin) Alterations, Body Mass Index, and Physical Activity with Survival in Patients with Colorectal Cancer

CONTEXT: Alterations of WNT-CTNNB1 (β-catenin) signaling play roles in colorectal carcinogenesis and metabolic diseases. OBJECTIVE: To test the hypothesis that CTNNB1 activation in colorectal cancer might modify prognostic associations of body mass index (BMI) and post-diagnosis physical activity. D...

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Autori principali: Morikawa, Teppei, Kuchiba, Aya, Yamauchi, Mai, Meyerhardt, Jeffrey A., Shima, Kaori, Nosho, Katsuhiko, Chan, Andrew T., Giovannucci, Edward, Fuchs, Charles S., Ogino, Shuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087286/
https://ncbi.nlm.nih.gov/pubmed/21521850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2011.513
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