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Mutator phenotypes due to DNA replication infidelity

This article considers the fidelity of DNA replication performed by eukaryotic DNA polymerases involved in replicating the nuclear genome. DNA replication fidelity can vary widely depending on the DNA polymerase, the composition of the error, the flanking sequence, the presence of DNA damage and the...

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Main Authors: Arana, Mercedes E., Kunkel, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087159/
https://ncbi.nlm.nih.gov/pubmed/20934516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.10.003
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