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Mutator phenotypes due to DNA replication infidelity

This article considers the fidelity of DNA replication performed by eukaryotic DNA polymerases involved in replicating the nuclear genome. DNA replication fidelity can vary widely depending on the DNA polymerase, the composition of the error, the flanking sequence, the presence of DNA damage and the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arana, Mercedes E., Kunkel, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087159/
https://ncbi.nlm.nih.gov/pubmed/20934516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.10.003
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