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Replication infidelity via a mismatch with Watson–Crick geometry
In describing the DNA double helix, Watson and Crick suggested that “spontaneous mutation may be due to a base occasionally occurring in one of its less likely tautomeric forms.” Indeed, among many mispairing possibilities, either tautomerization or ionization of bases might allow a DNA polymerase t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033279/ https://ncbi.nlm.nih.gov/pubmed/21233421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012825108 |
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