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Competition between Intradomain and Interdomain Interactions: A Buried Salt Bridge is Essential for Villin Headpiece Folding and Actin-Binding

Villin-type headpiece domains are ~70 residue motifs that reside at the C-terminus of a variety of actin-associated proteins. Villin headpiece (HP67) is a commonly used model system for both experimental and computational studies of protein folding. HP67 is made up of two subdomains that form a tigh...

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Hlavní autoři: Packer, Laura E., Song, Benben, Raleigh, Daniel P., McKnight, C. James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086997/
https://ncbi.nlm.nih.gov/pubmed/21449557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1020343
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