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Competition between Intradomain and Interdomain Interactions: A Buried Salt Bridge is Essential for Villin Headpiece Folding and Actin-Binding
Villin-type headpiece domains are ~70 residue motifs that reside at the C-terminus of a variety of actin-associated proteins. Villin headpiece (HP67) is a commonly used model system for both experimental and computational studies of protein folding. HP67 is made up of two subdomains that form a tigh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086997/ https://ncbi.nlm.nih.gov/pubmed/21449557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1020343 |
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