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On the unyielding hydrophobic core of villin headpiece

Villin headpiece (HP67) is a small, autonomously-folding domain that has become a model system for understanding the fundamental tenets governing protein folding. In this communication, we explore the role that Leu61 plays in the structure and stability of the construct. Deletion of Leu61 results in...

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Autores principales: Brown, Jeffrey W, Farelli, Jeremiah D, McKnight, C James
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403462/
https://ncbi.nlm.nih.gov/pubmed/22467489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2048
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