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On the unyielding hydrophobic core of villin headpiece

Villin headpiece (HP67) is a small, autonomously-folding domain that has become a model system for understanding the fundamental tenets governing protein folding. In this communication, we explore the role that Leu61 plays in the structure and stability of the construct. Deletion of Leu61 results in...

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Detalhes bibliográficos
Main Authors: Brown, Jeffrey W, Farelli, Jeremiah D, McKnight, C James
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403462/
https://ncbi.nlm.nih.gov/pubmed/22467489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2048
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