Identification of a Novel TGFβ/PKA Signaling Transduceome in Mediating Control of Cell Survival and Metastasis in Colon Cancer

BACKGROUND: Understanding drivers for metastasis in human cancer is important for potential development of therapies to treat metastases. The role of loss of TGFβ tumor suppressor activities in the metastatic process is essentially unknown. METHODOLOGY/PRINCIPAL FINDINGS: Utilizing in vitro and in v...

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Autori principali: Chowdhury, Sanjib, Howell, Gillian M., Rajput, Ashwani, Teggart, Carol A., Brattain, Lisa E., Weber, Hannah R., Chowdhury, Aparajita, Brattain, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086924/
https://ncbi.nlm.nih.gov/pubmed/21559296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019335
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