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Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation
Leukemogenesis requires two classes of mutations, one that promotes proliferation and one that blocks differentiation. The erythroleukemia induced by Friend virus is a multistage disease characterized by an early proliferative stage driven by the interaction of the viral glycoprotein, gp55, with Sf-...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086737/ https://ncbi.nlm.nih.gov/pubmed/19581930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.202 |
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