Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation

Leukemogenesis requires two classes of mutations, one that promotes proliferation and one that blocks differentiation. The erythroleukemia induced by Friend virus is a multistage disease characterized by an early proliferative stage driven by the interaction of the viral glycoprotein, gp55, with Sf-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hegde, S, Ni, S, He, S, Yoon, D, Feng, GS, Watowich, SS, Paulson, RF, Hankey, PA
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086737/
https://ncbi.nlm.nih.gov/pubmed/19581930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.202
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