Human cytomegalovirus decreases constitutive transcription of MHC class II genes in mature Langerhans cells by reducing CIITA transcript levels

Human cytomegalovirus (HCMV) productively infects CD34(+) progenitor-derived, mature Langerhans-type dendritic cells (matLC) and reduces surface expression of MHC class II complexes (MHC II) by increasing intracellular retention of these molecules. To determine whether HCMV also inhibits MHC II expr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lee, Andrew W., Wang, Nan, Hornell, Tara M.C., Harding, James J., Deshpande, Chetan, Hertel, Laura, Lacaille, Vashti, Pashine, Achal, Macaubas, Claudia, Mocarski, Edward S., Mellins, Elizabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086682/
https://ncbi.nlm.nih.gov/pubmed/21458073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.02.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados