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Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation

Transcription of the major histocompatibility complex class II family of genes is regulated by conserved promoter elements and two gene-specific trans-activators, RFX and CIITA. RFX binds DNA and nucleates the assembly of an enhanceosome, which recruits CIITA through protein–protein interactions. Tr...

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Autors principals: Masternak, Krzysztof, Reith, Walter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125922/
https://ncbi.nlm.nih.gov/pubmed/11889043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1379
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