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Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation

Transcription of the major histocompatibility complex class II family of genes is regulated by conserved promoter elements and two gene-specific trans-activators, RFX and CIITA. RFX binds DNA and nucleates the assembly of an enhanceosome, which recruits CIITA through protein–protein interactions. Tr...

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Autores principales: Masternak, Krzysztof, Reith, Walter
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC125922/
https://ncbi.nlm.nih.gov/pubmed/11889043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1379
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