Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation
Transcription of the major histocompatibility complex class II family of genes is regulated by conserved promoter elements and two gene-specific trans-activators, RFX and CIITA. RFX binds DNA and nucleates the assembly of an enhanceosome, which recruits CIITA through protein–protein interactions. Tr...
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| Опубликовано в:: | EMBO J |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11889043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.6.1379 |
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