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Preparation of a Library of Unsymmetrical Ureas Based on 8-Azabicyclo [3.2.1]Octane Scaffold
This paper reports the preparation of a library of unsymmetrical ureas based on 8-azabicyclo [3.2.1]octane scaffold. The reported synthetic route uses nortropane-8-carbonyl chlorides as key intermediates that, when treated with a slight excess of amine, give the corresponding ureas in high yield (12...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086471/ https://ncbi.nlm.nih.gov/pubmed/18611055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc800068k |
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