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A new constrained proline analogue with an 8-azabicyclo[3.2.1]octane skeleton

A straightforward synthesis of 8-azabicyclo[3.2.1]octane-1-carboxylic acid, a new proline analogue with a bicyclic structure, is described. The procedure makes use of readily available starting materials and involves simple, high-yielding transformations.

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Bibliographic Details
Main Authors: Casabona, Diego, Jiménez, Ana I., Cativiela, Carlos
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515930/
https://ncbi.nlm.nih.gov/pubmed/18704201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.03.115
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